7UTC

Crystal structure of secondary alcohol dehydrogenases from the Thermoanaerobacter ethanolicus with NADP and transition-state analogue inhibitor DMSO

Replaces:  7JNQ

Summary for 7UTC

• Entry DOI: 10.2210/pdb7utc/pdb
• Descriptor: Secondary-alcohol dehydrogenase, ZINC ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... (5 entities in total)
• Functional Keywords: secondary alcohol dehydrogenases, transition-state analogue inhibitor, dmso, nadp, oxidoreductase
• Biological source: Thermoanaerobacter pseudethanolicus
• Total number of polymer chains: 4
• Total formula weight: 156621.15

Authors

Dinh, T.,Phillips, R. (deposition date: 2022-04-26, release date: 2022-05-04, Last modification date: 2023-10-18)

• Primary citation: Dinh, T.,Rahn, K.T.,Phillips, R.S.; Crystallographic snapshots of ternary complexes of thermophilic secondary alcohol dehydrogenase from Thermoanaerobacter pseudoethanolicus reveal the dynamics of ligand exchange and the proton relay network.; Proteins, 90:1570-1583, 2022; PubMed: 35357038; DOI: 10.1002/prot.26339

Experimental method

X-RAY DIFFRACTION (1.85 Å)