6PL3
TRK-A IN COMPLEX WITH LIGAND 2a
Experimental procedure
| Experimental method | SINGLE WAVELENGTH |
| Source type | SYNCHROTRON |
| Source details | DIAMOND BEAMLINE I02 |
| Synchrotron site | Diamond |
| Beamline | I02 |
| Temperature [K] | 100 |
| Detector technology | PIXEL |
| Collection date | 2016-01-28 |
| Detector | DECTRIS PILATUS 6M-F |
| Wavelength(s) | 0.9282 |
| Spacegroup name | P 31 1 2 |
| Unit cell lengths | 52.746, 52.746, 232.764 |
| Unit cell angles | 90.00, 90.00, 120.00 |
Refinement procedure
| Resolution | 45.000 - 3.000 |
| R-factor | 0.21124 |
| Rwork | 0.206 |
| R-free | 0.27225 |
| Structure solution method | MOLECULAR REPLACEMENT |
| RMSD bond length | 0.008 |
| RMSD bond angle | 0.998 |
| Data reduction software | XDS |
| Data scaling software | XSCALE |
| Refinement software | REFMAC (5.6.0117) |
Data quality characteristics
| Overall | Outer shell | |
| Low resolution limit [Å] | 77.590 | 3.250 |
| High resolution limit [Å] | 3.000 | 3.000 |
| Rmerge | 0.116 | 0.440 |
| Number of reflections | 7476 | |
| <I/σ(I)> | 10.28 | |
| Completeness [%] | 96.1 | 97.5 |
| Redundancy | 2.9 | 2.9 |
Crystallization Conditions
| crystal ID | method | pH | temperature | details |
| 1 | VAPOR DIFFUSION, HANGING DROP | 277.15 | pH 8.5 |
