6HVF

Kinase domain of cSrc in complex with compound 29B

Experimental procedure

Experimental method	SINGLE WAVELENGTH
Source type	SYNCHROTRON
Source details	SLS BEAMLINE X10SA
Synchrotron site	SLS
Beamline	X10SA
Temperature [K]	100
Detector technology	PIXEL
Collection date	2015-10-26
Detector	DECTRIS PILATUS 6M-F
Wavelength(s)	0.97856
Spacegroup name	P 1
Unit cell lengths	42.170, 62.970, 74.540
Unit cell angles	100.23, 91.64, 90.03

Refinement procedure

Resolution	43.657 - 2.100
R-factor	0.2124
Rwork	0.211
R-free	0.24510
RMSD bond length	0.004
RMSD bond angle	0.684
Data reduction software	XDS
Data scaling software	XSCALE
Phasing software	PHASER
Refinement software	PHENIX ((1.10_2155: ???))

Data quality characteristics

	Overall	Outer shell
Low resolution limit [Å]	50.000	2.200
High resolution limit [Å]	2.100	2.100
Number of reflections	42945
<I/σ(I)>	8.37
Completeness [%]	97.5
Redundancy	3.5

Crystallization Conditions

crystal ID	method	pH	temperature	details
1	VAPOR DIFFUSION, HANGING DROP	7	293	10% ethylene glycol, 10 mM sodium chloride, pH 7.0