6HVE
Kinase domain of cSrc in complex with compound 9
Experimental procedure
Experimental method | SINGLE WAVELENGTH |
Source type | SYNCHROTRON |
Source details | SLS BEAMLINE X10SA |
Synchrotron site | SLS |
Beamline | X10SA |
Temperature [K] | 100 |
Detector technology | PIXEL |
Collection date | 2017-02-06 |
Detector | PSI PILATUS 6M |
Wavelength(s) | 0.9779 |
Spacegroup name | P 1 |
Unit cell lengths | 42.140, 63.600, 74.490 |
Unit cell angles | 101.43, 90.81, 91.13 |
Refinement procedure
Resolution | 43.341 - 1.900 |
R-factor | 0.1784 |
Rwork | 0.177 |
R-free | 0.20280 |
RMSD bond length | 0.009 |
RMSD bond angle | 0.962 |
Data reduction software | XDS |
Data scaling software | XSCALE |
Phasing software | PHASER |
Refinement software | PHENIX ((1.10_2155: ???)) |
Data quality characteristics
Overall | Outer shell | |
Low resolution limit [Å] | 50.000 | 2.000 |
High resolution limit [Å] | 1.900 | 1.900 |
Number of reflections | 57602 | |
<I/σ(I)> | 12.82 | |
Completeness [%] | 96.4 | |
Redundancy | 3.5 |
Crystallization Conditions
crystal ID | method | pH | temperature | details |
1 | VAPOR DIFFUSION, HANGING DROP | 7 | 293 | 10% ethylene glycol, 10 mM sodium chloride, pH 7.0 |