6EW7
Crystal structure of the BCL6 BTB domain in complex with anilinopyrimidine ligand
Experimental procedure
| Experimental method | SINGLE WAVELENGTH |
| Source type | SYNCHROTRON |
| Source details | APS BEAMLINE 17-ID |
| Synchrotron site | APS |
| Beamline | 17-ID |
| Temperature [K] | 100 |
| Detector technology | PIXEL |
| Collection date | 2014-04-14 |
| Detector | DECTRIS PILATUS3 S 6M |
| Wavelength(s) | 0.9 |
| Spacegroup name | P 1 |
| Unit cell lengths | 30.780, 39.290, 55.430 |
| Unit cell angles | 83.98, 73.95, 67.11 |
Refinement procedure
| Resolution | 29.900 - 1.600 |
| R-factor | 0.208 |
| Rwork | 0.207 |
| R-free | 0.23600 |
| Structure solution method | MOLECULAR REPLACEMENT |
| RMSD bond length | 0.010 |
| RMSD bond angle | 1.020 |
| Data reduction software | XDS |
| Data scaling software | Aimless |
| Phasing software | PHASER |
| Refinement software | BUSTER (2.11.6) |
Data quality characteristics
| Overall | Outer shell | |
| Low resolution limit [Å] | 29.980 | 1.690 |
| High resolution limit [Å] | 1.600 | 1.600 |
| Number of reflections | 29001 | |
| <I/σ(I)> | 6 | 2.3 |
| Completeness [%] | 95.8 | 92.2 |
| Redundancy | 2.1 | 2 |
Crystallization Conditions
| crystal ID | method | pH | temperature | details |
| 1 | VAPOR DIFFUSION, SITTING DROP | 310 | unknown |
