6VQF

CRYSTAL STRUCTURE OF RAR-RELATED ORPHAN RECEPTOR C (NHIS-RORGT(244- 487)-L6-SRC1(678-692)) IN COMPLEX WITH AN INVERSE AGONIST

Experimental procedure

Experimental method	SINGLE WAVELENGTH
Source type	SYNCHROTRON
Source details	APS BEAMLINE 17-ID
Synchrotron site	APS
Beamline	17-ID
Temperature [K]	100
Detector technology	PIXEL
Collection date	2016-07-27
Detector	DECTRIS PILATUS 6M
Wavelength(s)	1.0
Spacegroup name	P 41 21 2
Unit cell lengths	61.507, 61.507, 157.911
Unit cell angles	90.00, 90.00, 90.00

Refinement procedure

Resolution	57.000 - 2.000
R-factor	0.2055
Rwork	0.203
R-free	0.24100
Structure solution method	MOLECULAR REPLACEMENT
Starting model (for MR)	6o98
RMSD bond length	0.008
RMSD bond angle	0.910
Data reduction software	HKL-2000
Data scaling software	Aimless
Refinement software	BUSTER (2.11.7 (3-OCT-2019))

Data quality characteristics

	Overall	Outer shell
Low resolution limit [Å]	157.910	2.250
High resolution limit [Å]	2.000	2.000
Rmerge	0.117	1.149
Number of reflections	14591	383
<I/σ(I)>	16	2.4
Completeness [%]	96.4	99.3
Redundancy	12.5	12.9

Crystallization Conditions

crystal ID	method	pH	temperature	details
1	VAPOR DIFFUSION, HANGING DROP		298	20-26% PEG3350, 0.2 M MAGNESIUM CHLORIDE, 0.1 M BIS-TRIS PH 5.5-6.5,