6HVE

Kinase domain of cSrc in complex with compound 9

Experimental procedure

Experimental method	SINGLE WAVELENGTH
Source type	SYNCHROTRON
Source details	SLS BEAMLINE X10SA
Synchrotron site	SLS
Beamline	X10SA
Temperature [K]	100
Detector technology	PIXEL
Collection date	2017-02-06
Detector	PSI PILATUS 6M
Wavelength(s)	0.9779
Spacegroup name	P 1
Unit cell lengths	42.140, 63.600, 74.490
Unit cell angles	101.43, 90.81, 91.13

Refinement procedure

Resolution	43.341 - 1.900
R-factor	0.1784
Rwork	0.177
R-free	0.20280
RMSD bond length	0.009
RMSD bond angle	0.962
Data reduction software	XDS
Data scaling software	XSCALE
Phasing software	PHASER
Refinement software	PHENIX ((1.10_2155: ???))

Data quality characteristics

	Overall	Outer shell
Low resolution limit [Å]	50.000	2.000
High resolution limit [Å]	1.900	1.900
Number of reflections	57602
<I/σ(I)>	12.82
Completeness [%]	96.4
Redundancy	3.5

Crystallization Conditions

crystal ID	method	pH	temperature	details
1	VAPOR DIFFUSION, HANGING DROP	7	293	10% ethylene glycol, 10 mM sodium chloride, pH 7.0