6DXK
Glucocorticoid Receptor in complex with Compound 11
Experimental procedure
Experimental method | SINGLE WAVELENGTH |
Source type | SYNCHROTRON |
Source details | SLS BEAMLINE X06SA |
Synchrotron site | SLS |
Beamline | X06SA |
Temperature [K] | 100 |
Detector technology | PIXEL |
Collection date | 2016-04-05 |
Detector | DECTRIS EIGER X 16M |
Wavelength(s) | 1 |
Spacegroup name | P 21 21 21 |
Unit cell lengths | 79.193, 98.694, 100.410 |
Unit cell angles | 90.00, 90.00, 90.00 |
Refinement procedure
Resolution | 49.350 - 3.050 |
R-factor | 0.21837 |
Rwork | 0.217 |
R-free | 0.25989 |
Structure solution method | MOLECULAR REPLACEMENT |
Starting model (for MR) | 1nhz |
RMSD bond length | 0.011 |
RMSD bond angle | 1.443 |
Data reduction software | XDS |
Data scaling software | XSCALE |
Phasing software | PHASER |
Refinement software | REFMAC (5.8.0155) |
Data quality characteristics
Overall | Outer shell | |
Low resolution limit [Å] | 70.390 | 3.300 |
High resolution limit [Å] | 3.050 | 3.050 |
Rmerge | 0.090 | 0.430 |
Number of reflections | 15142 | 3103 |
<I/σ(I)> | 17.7 | |
Completeness [%] | 97.5 | 97 |
Redundancy | 5 | 4.8 |
Crystallization Conditions
crystal ID | method | pH | temperature | details |
1 | VAPOR DIFFUSION | 293 | pH 6.75 |