6DXK
Glucocorticoid Receptor in complex with Compound 11
Experimental procedure
| Experimental method | SINGLE WAVELENGTH |
| Source type | SYNCHROTRON |
| Source details | SLS BEAMLINE X06SA |
| Synchrotron site | SLS |
| Beamline | X06SA |
| Temperature [K] | 100 |
| Detector technology | PIXEL |
| Collection date | 2016-04-05 |
| Detector | DECTRIS EIGER X 16M |
| Wavelength(s) | 1 |
| Spacegroup name | P 21 21 21 |
| Unit cell lengths | 79.193, 98.694, 100.410 |
| Unit cell angles | 90.00, 90.00, 90.00 |
Refinement procedure
| Resolution | 49.350 - 3.050 |
| R-factor | 0.21837 |
| Rwork | 0.217 |
| R-free | 0.25989 |
| Structure solution method | MOLECULAR REPLACEMENT |
| Starting model (for MR) | 1nhz |
| RMSD bond length | 0.011 |
| RMSD bond angle | 1.443 |
| Data reduction software | XDS |
| Data scaling software | XSCALE |
| Phasing software | PHASER |
| Refinement software | REFMAC (5.8.0155) |
Data quality characteristics
| Overall | Outer shell | |
| Low resolution limit [Å] | 70.390 | 3.300 |
| High resolution limit [Å] | 3.050 | 3.050 |
| Rmerge | 0.090 | 0.430 |
| Number of reflections | 15142 | 3103 |
| <I/σ(I)> | 17.7 | |
| Completeness [%] | 97.5 | 97 |
| Redundancy | 5 | 4.8 |
Crystallization Conditions
| crystal ID | method | pH | temperature | details |
| 1 | VAPOR DIFFUSION | 293 | pH 6.75 |
