6CO3
aducanumab abeta complex
Experimental procedure
| Experimental method | SINGLE WAVELENGTH |
| Source type | SYNCHROTRON |
| Source details | APS BEAMLINE 31-ID |
| Synchrotron site | APS |
| Beamline | 31-ID |
| Temperature [K] | 100 |
| Detector technology | CCD |
| Collection date | 2015-03-10 |
| Detector | MARMOSAIC 225 mm CCD |
| Wavelength(s) | .97931 |
| Spacegroup name | C 1 2 1 |
| Unit cell lengths | 141.659, 64.844, 67.280 |
| Unit cell angles | 90.00, 95.63, 90.00 |
Refinement procedure
| Resolution | 19.955 - 2.384 |
| R-factor | 0.1839 |
| Rwork | 0.181 |
| R-free | 0.23490 |
| Structure solution method | MOLECULAR REPLACEMENT |
| Starting model (for MR) | 6cnr |
| RMSD bond length | 0.003 |
| RMSD bond angle | 0.660 |
| Data reduction software | XDS |
| Data scaling software | SCALA |
| Phasing software | MOLREP |
| Refinement software | PHENIX ((1.13_2998: ???)) |
Data quality characteristics
| Overall | Outer shell | |
| Low resolution limit [Å] | 50.000 | 2.510 |
| High resolution limit [Å] | 2.380 | 2.380 |
| Rmerge | 0.068 | 0.281 |
| Number of reflections | 22692 | |
| <I/σ(I)> | 9 | |
| Completeness [%] | 93.1 | |
| Redundancy | 3.7 |
Crystallization Conditions
| crystal ID | method | pH | temperature | details |
| 1 | VAPOR DIFFUSION, SITTING DROP | 7 | 297 | 19% PEG 3350 in 100 mM sodium acetate, and 300 mM lithium sulfate |
