5YOV

Crystal structure of BRD4-BD1 bound with hjp126

Experimental procedure

Experimental method	SINGLE WAVELENGTH
Source type	SYNCHROTRON
Source details	SSRF BEAMLINE BL17U1
Synchrotron site	SSRF
Beamline	BL17U1
Temperature [K]	100
Detector technology	CCD
Collection date	2015-12-17
Detector	ADSC QUANTUM 315r
Wavelength(s)	0.97923
Spacegroup name	P 21 21 21
Unit cell lengths	32.340, 47.435, 78.926
Unit cell angles	90.00, 90.00, 90.00

Refinement procedure

Resolution	26.721 - 1.451
R-factor	0.1888
Rwork	0.186
R-free	0.23140
Structure solution method	MOLECULAR REPLACEMENT
RMSD bond length	0.007
RMSD bond angle	1.243
Data scaling software	XDS
Phasing software	PHASER
Refinement software	PHENIX (1.9_1692)

Data quality characteristics

	Overall
Low resolution limit [Å]	78.719
High resolution limit [Å]	1.451
Number of reflections	19355
<I/σ(I)>	21
Completeness [%]	87.7
Redundancy	5.73

Crystallization Conditions

crystal ID	method	pH	temperature	details
1	VAPOR DIFFUSION, HANGING DROP		293	3.6M Naformate, 10% glycerol