5HOA
Crystal structure of c-Met L1195V in complex with SAR125844
Experimental procedure
Experimental method | SINGLE WAVELENGTH |
Source type | SYNCHROTRON |
Source details | ESRF BEAMLINE ID14-4 |
Synchrotron site | ESRF |
Beamline | ID14-4 |
Temperature [K] | 100 |
Detector technology | CCD |
Collection date | 2009-01-28 |
Detector | ADSC QUANTUM 315 |
Wavelength(s) | 0.9185 |
Spacegroup name | P 21 21 21 |
Unit cell lengths | 42.880, 47.550, 153.650 |
Unit cell angles | 90.00, 90.00, 90.00 |
Refinement procedure
Resolution | 31.850 - 2.140 |
Data reduction software | MOSFLM |
Data scaling software | SCALA |
Phasing software | AMoRE |
Refinement software | REFMAC |
Data quality characteristics
Overall | Outer shell | |
Low resolution limit [Å] | 47.570 | 2.250 |
High resolution limit [Å] | 2.140 | 2.140 |
Number of reflections | 58760 | |
<I/σ(I)> | 10.6 | 2.6 |
Completeness [%] | 98.3 | 99.3 |
Redundancy | 3.3 | 3.3 |
Crystallization Conditions
crystal ID | method | pH | temperature | details |
1 | VAPOR DIFFUSION, HANGING DROP | 8.5 | 277 | Tris 100 mM, MPD 24%, pH8.5 |