5FSK

MTH1 substrate recognition: Complex with 8-oxo-dGTP.

Experimental procedure

Experimental method	SINGLE WAVELENGTH
Source type	SYNCHROTRON
Source details	DIAMOND BEAMLINE I04
Synchrotron site	Diamond
Beamline	I04
Temperature [K]	100
Spacegroup name	P 21 21 2
Unit cell lengths	60.495, 65.608, 36.348
Unit cell angles	90.00, 90.00, 90.00

Refinement procedure

Resolution	44.470 - 1.560
R-factor	0.2055
Rwork	0.204
R-free	0.24240
Structure solution method	OTHER
RMSD bond length	0.010
RMSD bond angle	1.110
Refinement software	BUSTER (2.11.6)

Data quality characteristics

	Overall	Outer shell
Low resolution limit [Å]	60.500	1.750
High resolution limit [Å]	1.560	1.560
Rmerge	0.050
Number of reflections	21044
<I/σ(I)>	21
Completeness [%]	99.6	98.7
Redundancy	4

Crystallization Conditions

crystal ID	method	pH	temperature	details
1