5SVF

IDH1 R132H in complex with IDH125

Experimental procedure

Experimental method	SINGLE WAVELENGTH
Source type	SYNCHROTRON
Source details	APS BEAMLINE 17-ID
Synchrotron site	APS
Beamline	17-ID
Temperature [K]	100
Detector technology	PIXEL
Collection date	2011-03-11
Detector	DECTRIS PILATUS3 S 6M
Wavelength(s)	1.0
Spacegroup name	P 21 21 21
Unit cell lengths	81.979, 154.993, 162.989
Unit cell angles	90.00, 90.00, 90.00

Refinement procedure

Resolution	40.750 - 2.340
Rwork	0.179
R-free	0.22320
Data reduction software	XDS
Data scaling software	autoPROC
Phasing software	PHENIX
Refinement software	PHENIX

Data quality characteristics

	Overall
Low resolution limit [Å]	162.990
High resolution limit [Å]	2.340
Number of reflections	88813
<I/σ(I)>	17.7
Completeness [%]	100.0
Redundancy	6.7

Crystallization Conditions

crystal ID	method	pH	temperature	details
1	VAPOR DIFFUSION, HANGING DROP		293	0.1M Bis-Tris pH6.5, 1.45M tri-sodium citrate dihydrate