5L6Y
il13 in complex with tralokinumab
Experimental procedure
| Experimental method | SINGLE WAVELENGTH |
| Source type | SYNCHROTRON |
| Source details | DIAMOND BEAMLINE I03 |
| Synchrotron site | Diamond |
| Beamline | I03 |
| Temperature [K] | 100 |
| Detector technology | PIXEL |
| Collection date | 2015-10-16 |
| Detector | DECTRIS PILATUS3 6M |
| Wavelength(s) | 0.9749 |
| Spacegroup name | P 1 |
| Unit cell lengths | 50.998, 53.195, 62.050 |
| Unit cell angles | 107.91, 101.42, 96.94 |
Refinement procedure
| Resolution | 49.650 - 1.990 |
| R-factor | 0.19 |
| Rwork | 0.189 |
| R-free | 0.21100 |
| Structure solution method | MOLECULAR REPLACEMENT |
| Starting model (for MR) | in-house model |
| RMSD bond length | 0.022 |
| RMSD bond angle | 1.180 |
| Data reduction software | XDS |
| Data scaling software | XDS |
| Phasing software | PHASER |
| Refinement software | BUSTER (2.11.6) |
Data quality characteristics
| Overall | Outer shell | |
| Low resolution limit [Å] | 49.650 | 2.100 |
| High resolution limit [Å] | 1.990 | 1.990 |
| Rmerge | 0.130 | 0.320 |
| Number of reflections | 39821 | |
| <I/σ(I)> | 11.7 | 2.1 |
| Completeness [%] | 97.7 | 93.4 |
| Redundancy | 10.5 | 7.1 |
Crystallization Conditions
| crystal ID | method | pH | temperature | details |
| 1 | VAPOR DIFFUSION, HANGING DROP | 293 | sodium formate |
