5HOR

Crystal structure of c-Met-M1250T in complex with SAR125844.

Experimental procedure

Experimental method	SINGLE WAVELENGTH
Source type	SYNCHROTRON
Source details	ESRF BEAMLINE ID23-1
Synchrotron site	ESRF
Beamline	ID23-1
Temperature [K]	100
Detector technology	CCD
Collection date	2009-02-15
Detector	ADSC QUANTUM 315
Wavelength(s)	1.07230
Spacegroup name	P 21 21 21
Unit cell lengths	43.020, 46.990, 156.620
Unit cell angles	90.00, 90.00, 90.00

Refinement procedure

Resolution	39.100 - 2.200
Data reduction software	MOSFLM
Data scaling software	SCALA
Phasing software	AMoRE
Refinement software	BUSTER-TNT

Data quality characteristics

	Overall
Low resolution limit [Å]	39.100
High resolution limit [Å]	2.200
Number of reflections	16185
<I/σ(I)>	13.5
Completeness [%]	99.6
Redundancy	4.3

Crystallization Conditions

crystal ID	method	pH	temperature	details
1	VAPOR DIFFUSION, HANGING DROP	8.5	277	Tris 100mM, MPD 20%, pH8.5