5ABW
Neutrophil elastase inhibitors for the treatment of (cardio)pulmonary diseases
Experimental procedure
| Experimental method | SINGLE WAVELENGTH |
| Source type | ROTATING ANODE |
| Source details | PROTEUM |
| Temperature [K] | 100 |
| Detector technology | CCD |
| Collection date | 2007-11-27 |
| Detector | BRUKER |
| Spacegroup name | P 63 |
| Unit cell lengths | 73.225, 73.225, 70.475 |
| Unit cell angles | 90.00, 90.00, 120.00 |
Refinement procedure
| Resolution | 63.370 - 1.600 |
| R-factor | 0.15971 |
| Rwork | 0.158 |
| R-free | 0.19422 |
| Structure solution method | MOLECULAR REPLACEMENT |
| Data reduction software | SAINT |
| Data scaling software | SADABS |
| Phasing software | MOLREP |
| Refinement software | REFMAC (5.2.0019) |
Data quality characteristics
| Overall | Outer shell | |
| Low resolution limit [Å] | 32.490 | 1.700 |
| High resolution limit [Å] | 1.600 | 1.600 |
| Rmerge | 0.060 | 0.370 |
| Number of reflections | 28396 | |
| <I/σ(I)> | 26.24 | 4.87 |
| Completeness [%] | 100.0 | 100 |
| Redundancy | 13.18 | 6.96 |
Crystallization Conditions
| crystal ID | method | pH | temperature | details |
| 1 |
