4ZSC

Human Cyclophilin D Complexed with an Inhibitor at room temperature

Experimental procedure

Experimental method	SINGLE WAVELENGTH
Source type	SYNCHROTRON
Source details	ESRF BEAMLINE BM30A
Synchrotron site	ESRF
Beamline	BM30A
Temperature [K]	298
Detector technology	CCD
Collection date	2015-05-07
Detector	ADSC QUANTUM 315r
Wavelength(s)	0.9797
Spacegroup name	P 41 21 2
Unit cell lengths	57.866, 57.866, 88.463
Unit cell angles	90.00, 90.00, 90.00

Refinement procedure

Resolution	48.430 - 1.500
R-factor	0.135
Rwork	0.134
R-free	0.16280
RMSD bond length	0.007
RMSD bond angle	1.300
Data reduction software	XDS
Data scaling software	SCALA
Phasing software	REFMAC
Refinement software	REFMAC (5.8.0103)

Data quality characteristics

	Overall
Low resolution limit [Å]	48.400
High resolution limit [Å]	1.500
Number of reflections	16982
<I/σ(I)>	12.1
Completeness [%]	73.1
Redundancy	2.8

Crystallization Conditions

crystal ID	method	pH	temperature	details
1	VAPOR DIFFUSION, SITTING DROP	7.3	291	30% PEG4000