4U5U

IMPORTIN-ALPHA MINOR NLS SITE INHIBITOR

Experimental procedure

Experimental method	SINGLE WAVELENGTH
Source type	SYNCHROTRON
Source details	ESRF BEAMLINE ID14-4
Synchrotron site	ESRF
Beamline	ID14-4
Temperature [K]	100
Detector technology	CCD
Collection date	2013-09-28
Detector	ADSC QUANTUM 315r
Wavelength(s)	0.9763
Spacegroup name	P 21 21 21
Unit cell lengths	78.667, 90.469, 100.082
Unit cell angles	90.00, 90.00, 90.00

Refinement procedure

Resolution	36.608 - 1.960
R-factor	0.1965
Rwork	0.195
R-free	0.21550
RMSD bond length	0.008
RMSD bond angle	1.248
Refinement software	PHENIX ((phenix.refine: dev_1702))

Data quality characteristics

	Overall
Low resolution limit [Å]	67.100
High resolution limit [Å]	1.960
Number of reflections	51660
<I/σ(I)>	14.8
Completeness [%]	99.6
Redundancy	4.8

Crystallization Conditions

crystal ID	method	pH	temperature	details
1	VAPOR DIFFUSION, HANGING DROP		291	see manuscript