4U5N

IMPORTIN-ALPHA MINOR NLS SITE INHIBITOR

Experimental procedure

Experimental method	SINGLE WAVELENGTH
Source type	SYNCHROTRON
Source details	ESRF BEAMLINE ID14-4
Synchrotron site	ESRF
Beamline	ID14-4
Temperature [K]	100
Detector technology	CCD
Collection date	2013-09-28
Detector	ADSC QUANTUM 315r
Wavelength(s)	0.919
Spacegroup name	P 21 21 21
Unit cell lengths	78.501, 91.080, 98.965
Unit cell angles	90.00, 90.00, 90.00

Refinement procedure

Resolution	45.540 - 2.310
R-factor	0.1886
Rwork	0.187
R-free	0.22130
RMSD bond length	0.009
RMSD bond angle	1.254
Refinement software	PHENIX ((phenix.refine: dev_1702))

Data quality characteristics

	Overall
Low resolution limit [Å]	67.000
High resolution limit [Å]	2.300
Number of reflections	31713
<I/σ(I)>	13.4
Completeness [%]	99.8
Redundancy	7.8

Crystallization Conditions

crystal ID	method	pH	temperature	details
1	VAPOR DIFFUSION, HANGING DROP		291	see manuscript