4L90

Crystal structure of Human Hsp90 with RL3

Experimental procedure

Experimental method	SINGLE WAVELENGTH
Source type	SYNCHROTRON
Source details	SSRF BEAMLINE BL17U
Synchrotron site	SSRF
Beamline	BL17U
Temperature [K]	100
Detector technology	CCD
Detector	ADSC QUANTUM 315r
Wavelength(s)	0.9792
Spacegroup name	I 2 2 2
Unit cell lengths	69.880, 88.588, 97.982
Unit cell angles	90.00, 90.00, 90.00

Refinement procedure

Resolution	36.543 - 2.001
R-factor	0.1906
Rwork	0.188
R-free	0.21940
Structure solution method	MOLECULAR REPLACEMENT
Starting model (for MR)	3t0z
RMSD bond length	0.007
RMSD bond angle	1.098
Data reduction software	HKL-2000
Data scaling software	HKL-2000
Phasing software	PHENIX
Refinement software	PHENIX ((phenix.refine: 1.8.1_1168))

Data quality characteristics

	Overall
Low resolution limit [Å]	36.543
High resolution limit [Å]	2.000
Number of reflections	20890
Completeness [%]	99.8

Crystallization Conditions

crystal ID	method	pH	temperature	details
1