4I2Q
Crystal structure of K103N/Y181C mutant of HIV-1 reverse transcriptase in complex with rilpivirine (TMC278) analogue
Experimental procedure
Experimental method | SINGLE WAVELENGTH |
Source type | SYNCHROTRON |
Source details | CHESS BEAMLINE F1 |
Synchrotron site | CHESS |
Beamline | F1 |
Detector technology | CCD |
Collection date | 2010-07-13 |
Detector | ADSC QUANTUM 270 |
Spacegroup name | C 1 2 1 |
Unit cell lengths | 162.602, 72.953, 108.543 |
Unit cell angles | 90.00, 100.70, 90.00 |
Refinement procedure
Resolution | 43.015 - 2.700 |
R-factor | 0.2146 |
Rwork | 0.211 |
R-free | 0.27680 |
Structure solution method | MOLECULAR REPLACEMENT |
RMSD bond length | 0.009 |
RMSD bond angle | 1.263 |
Data reduction software | HKL-2000 |
Data scaling software | HKL-2000 |
Phasing software | PHENIX (1.7.1_743) |
Refinement software | PHENIX ((phenix.refine: 1.7.1_743)) |
Data quality characteristics
Overall | |
Low resolution limit [Å] | 43.015 |
High resolution limit [Å] | 2.700 |
Number of reflections | 34228 |
Crystallization Conditions
crystal ID | method | pH | temperature | details |
1 |