4BB4
ephB4 kinase domain inhibitor complex
Experimental procedure
| Experimental method | SINGLE WAVELENGTH |
| Source type | ROTATING ANODE |
| Source details | RIGAKU FR-E |
| Temperature [K] | 100 |
| Detector technology | CCD |
| Collection date | 2006-05-02 |
| Detector | RIGAKU CCD |
| Spacegroup name | P 1 21 1 |
| Unit cell lengths | 46.421, 53.329, 61.209 |
| Unit cell angles | 90.00, 111.50, 90.00 |
Refinement procedure
| Resolution | 21.280 - 1.650 |
| R-factor | 0.2087 |
| Rwork | 0.207 |
| R-free | 0.23610 |
| Structure solution method | MOLECULAR REPLACEMENT |
| Data reduction software | d*TREK |
| Data scaling software | d*TREK |
| Phasing software | AMoRE |
| Refinement software | BUSTER-TNT (2.11.2) |
Data quality characteristics
| Overall | Outer shell | |
| Low resolution limit [Å] | 100.000 | 1.700 |
| High resolution limit [Å] | 1.650 | 1.650 |
| Rmerge | 0.040 | 0.360 |
| Number of reflections | 29124 | |
| <I/σ(I)> | 13.2 | 1.8 |
| Completeness [%] | 86.7 | 33.4 |
| Redundancy | 3.27 | 1.7 |
Crystallization Conditions
| crystal ID | method | pH | temperature | details |
| 1 | 7.4 | pH 7.4 |
