4UMP
Structure of MELK in complex with inhibitors
Experimental procedure
| Experimental method | SINGLE WAVELENGTH |
| Source type | ROTATING ANODE |
| Source details | RIGAKU FR-E |
| Temperature [K] | 100 |
| Detector technology | IMAGE PLATE |
| Collection date | 2010-05-02 |
| Detector | RIGAKU IMAGE PLATE RAXIS |
| Spacegroup name | P 1 |
| Unit cell lengths | 65.822, 74.968, 77.088 |
| Unit cell angles | 86.47, 70.06, 89.94 |
Refinement procedure
| Resolution | 50.380 - 2.300 |
| R-factor | 0.2378 |
| Rwork | 0.235 |
| R-free | 0.29100 |
| Structure solution method | OTHER |
| Starting model (for MR) | NONE |
| RMSD bond length | 0.011 |
| RMSD bond angle | 0.940 |
| Data reduction software | d*TREK |
| Data scaling software | d*TREK |
| Refinement software | BUSTER (2.11.5) |
Data quality characteristics
| Overall | |
| Low resolution limit [Å] | 50.000 |
| High resolution limit [Å] | 2.300 |
| Rmerge | 0.070 |
| Number of reflections | 61286 |
| <I/σ(I)> | 5.7 |
| Completeness [%] | 95.8 |
| Redundancy | 1.95 |
Crystallization Conditions
| crystal ID | method | pH | temperature | details |
| 1 |
