4U5S

IMPORTIN-ALPHA MINOR NLS SITE INHIBITOR

Experimental procedure

Experimental method	SINGLE WAVELENGTH
Source type	SYNCHROTRON
Source details	DIAMOND BEAMLINE I04-1
Synchrotron site	Diamond
Beamline	I04-1
Temperature [K]	100
Detector technology	PIXEL
Collection date	2013-10-25
Detector	PSI PILATUS 6M
Wavelength(s)	0.9200
Spacegroup name	P 21 21 21
Unit cell lengths	79.630, 91.330, 102.180
Unit cell angles	90.00, 90.00, 90.00

Refinement procedure

Resolution	20.007 - 2.120
R-factor	0.2
Rwork	0.198
R-free	0.23070
Data reduction software	XSCALE
Refinement software	PHENIX

Data quality characteristics

	Overall
Low resolution limit [Å]	68.200
High resolution limit [Å]	2.100
Number of reflections	42601
<I/σ(I)>	24.1
Completeness [%]	99.2
Redundancy	8.5

Crystallization Conditions

crystal ID	method	pH	temperature	details
1	VAPOR DIFFUSION, HANGING DROP		291	see manuscript