4N79

Structure of Cathepsin K-dermatan sulfate complex

Experimental procedure

Experimental method	SINGLE WAVELENGTH
Source type	SYNCHROTRON
Source details	SSRL BEAMLINE BL7-1
Synchrotron site	SSRL
Beamline	BL7-1
Temperature [K]	100
Spacegroup name	P 21 21 21
Unit cell lengths	31.830, 67.290, 90.800
Unit cell angles	90.00, 90.00, 90.00

Refinement procedure

Resolution	37.640 - 2.620
R-factor	0.23
Rwork	0.228
R-free	0.26000
Structure solution method	MOLECULAR REPLACEMENT
RMSD bond length	0.006
RMSD bond angle	1.513
Data reduction software	MOSFLM
Data scaling software	SCALA
Refinement software	REFMAC (5.7.0029)

Data quality characteristics

	Overall
Low resolution limit [Å]	67.290
High resolution limit [Å]	2.620
Number of reflections	6224

Crystallization Conditions

crystal ID	method	pH	temperature	details
1	VAPOR DIFFUSION			VAPOR DIFFUSION