4LYN

Crystal structure of cyclin-dependent kinase 2 (cdk2-wt) complex with (2s)-n-(5-(((5-tert-butyl-1,3-oxazol-2-yl)methyl)sulfanyl)-1,3-thiazol-2-yl)-2-phenylpropanamide

Experimental procedure

Experimental method	SINGLE WAVELENGTH
Source type	ROTATING ANODE
Source details	RIGAKU
Temperature [K]	100
Detector technology	HI-STAR
Collection date	1998-01-23
Detector	SIEMENS
Wavelength(s)	1.54
Spacegroup name	P 21 21 21
Unit cell lengths	53.460, 71.840, 72.190
Unit cell angles	90.00, 90.00, 90.00

Refinement procedure

Resolution	19.970 - 2.000
R-factor	0.1874
Rwork	0.185
R-free	0.23780
Structure solution method	MOLECULAR REPLACEMENT
Starting model (for MR)	CDK2 NATIVE
RMSD bond length	0.010
RMSD bond angle	1.010
Data reduction software	X-GEN
Data scaling software	X-GEN
Phasing software	AMoRE
Refinement software	BUSTER (2.11.5)

Data quality characteristics

	Overall
Low resolution limit [Å]	25.000
High resolution limit [Å]	2.000
Number of reflections	18817
Completeness [%]	98.2

Crystallization Conditions

crystal ID	method	pH	temperature	details
1