4A95
Plasmodium vivax N-myristoyltransferase with quinoline inhibitor
Experimental procedure
| Experimental method | SINGLE WAVELENGTH |
| Source type | SYNCHROTRON |
| Source details | ESRF BEAMLINE ID14-4 |
| Synchrotron site | ESRF |
| Beamline | ID14-4 |
| Temperature [K] | 100 |
| Detector technology | CCD |
| Collection date | 2011-03-07 |
| Detector | ADSC CCD |
| Spacegroup name | P 21 21 21 |
| Unit cell lengths | 57.490, 121.560, 179.010 |
| Unit cell angles | 90.00, 90.00, 90.00 |
Refinement procedure
| Resolution | 72.080 - 1.550 |
| R-factor | 0.18897 |
| Rwork | 0.186 |
| R-free | 0.23596 |
| Structure solution method | MOLECULAR REPLACEMENT |
| Starting model (for MR) | PVNMT |
| RMSD bond length | 0.024 |
| RMSD bond angle | 2.083 |
| Data reduction software | XDS |
| Data scaling software | XSCALE |
| Phasing software | MOLREP |
| Refinement software | REFMAC (5.6.0116) |
Data quality characteristics
| Overall | Outer shell | |
| Low resolution limit [Å] | 72.000 | 1.590 |
| High resolution limit [Å] | 1.550 | 1.550 |
| Rmerge | 0.090 | 0.350 |
| Number of reflections | 154218 | |
| <I/σ(I)> | 15.6 | 2.3 |
| Completeness [%] | 85.2 | 46.6 |
| Redundancy | 8.1 | 2.6 |
Crystallization Conditions
| crystal ID | method | pH | temperature | details |
| 1 | 6 | 0.2 M AS, 25% PEG 3350, 0.1 M BIS-TRIS PH 6.0 |
