3CIZ

Crystal structure of hepatitis c virus rna-dependent rna polymerase ns5b in complex with small molecule fragments

Experimental procedure

Experimental method	SINGLE WAVELENGTH
Source type	SYNCHROTRON
Source details	APS BEAMLINE 31-ID
Synchrotron site	APS
Beamline	31-ID
Temperature [K]	100
Detector technology	CCD
Collection date	2005-04-10
Detector	MAR CCD 165 mm
Wavelength(s)	0.91998
Spacegroup name	P 21 21 21
Unit cell lengths	86.055, 106.454, 127.051
Unit cell angles	90.00, 90.00, 90.00

Refinement procedure

Resolution	? - 1.870
Rwork	0.191
R-free	0.23500
Refinement software	REFMAC

Data quality characteristics

	Overall
Low resolution limit [Å]	26.000
High resolution limit [Å]	1.870
Number of reflections	95879

Crystallization Conditions

crystal ID	method	pH	temperature	details
1	VAPOR DIFFUSION	4.9	292	8-11% GLYCEROL, 20-24% PEG 4000,50 mM Sodium CITRATE, pH 4.9, VAPOR DIFFUSION, temperature 292K