3ZNR
HDAC7 bound with inhibitor TMP269
Experimental procedure
| Experimental method | SINGLE WAVELENGTH |
| Source type | SYNCHROTRON |
| Source details | APS BEAMLINE 21-ID-G |
| Synchrotron site | APS |
| Beamline | 21-ID-G |
| Temperature [K] | 100 |
| Detector technology | CCD |
| Collection date | 2011-06-08 |
| Detector | MARRESEARCH MX-300 |
| Spacegroup name | P 32 |
| Unit cell lengths | 81.393, 81.393, 149.265 |
| Unit cell angles | 90.00, 90.00, 120.00 |
Refinement procedure
| Resolution | 70.490 - 2.400 |
| R-factor | 0.21385 |
| Rwork | 0.212 |
| R-free | 0.24102 |
| Structure solution method | MOLECULAR REPLACEMENT |
| RMSD bond length | 0.005 |
| RMSD bond angle | 0.812 |
| Data reduction software | HKL |
| Data scaling software | HKL |
| Phasing software | PHASER |
| Refinement software | REFMAC (5.5.0109) |
Data quality characteristics
| Overall | Outer shell | |
| Low resolution limit [Å] | 30.000 | 2.430 |
| High resolution limit [Å] | 2.350 | 2.350 |
| Rmerge | 0.070 | 0.600 |
| Number of reflections | 40790 | |
| <I/σ(I)> | 18.8 | 2.1 |
| Completeness [%] | 99.0 | 98.1 |
| Redundancy | 4.4 | 4.1 |
Crystallization Conditions
| crystal ID | method | pH | temperature | details |
| 1 | 7.5 | pH 7.5 |
