3ZL7
BACE2 FYNOMER COMPLEX
Experimental procedure
| Experimental method | SINGLE WAVELENGTH |
| Source type | SYNCHROTRON |
| Source details | SLS BEAMLINE X10SA |
| Synchrotron site | SLS |
| Beamline | X10SA |
| Temperature [K] | 100 |
| Detector technology | PIXEL |
| Collection date | 2011-03-17 |
| Detector | DECTRIS PILATUS 6M |
| Spacegroup name | P 43 21 2 |
| Unit cell lengths | 84.793, 84.793, 128.113 |
| Unit cell angles | 90.00, 90.00, 90.00 |
Refinement procedure
| Resolution | 43.770 - 3.200 |
| R-factor | 0.2804 |
| Rwork | 0.279 |
| R-free | 0.30580 |
| Structure solution method | MOLECULAR REPLACEMENT |
| Starting model (for MR) | PDB ENTRIES 3ZKQ 4ag1 |
| RMSD bond length | 0.007 |
| RMSD bond angle | 0.940 |
| Data reduction software | XDS |
| Data scaling software | SADABS |
| Phasing software | PHASER |
| Refinement software | BUSTER (2.11.2) |
Data quality characteristics
| Overall | Outer shell | |
| Low resolution limit [Å] | 43.770 | 3.010 |
| High resolution limit [Å] | 2.910 | 2.910 |
| Rmerge | 0.130 | 0.740 |
| Number of reflections | 10238 | |
| <I/σ(I)> | 12.9 | 1.9 |
| Completeness [%] | 94.5 | 100 |
| Redundancy | 11.6 | 12.7 |
Crystallization Conditions
| crystal ID | method | pH | temperature | details |
| 1 | 5 | 1.8M NA/K PHOSPHATE, PH 5.0 |
