3S2P

Crystal structure of CDK2 with a 2-aminopyrimidine compound

Experimental procedure

Experimental method	SINGLE WAVELENGTH
Source type	ROTATING ANODE
Source details	MACSCIENCE
Temperature [K]	100
Detector technology	IMAGE PLATE
Collection date	2002-04-23
Detector	MAC Science DIP-2030
Wavelength(s)	1.54
Spacegroup name	P 21 21 21
Unit cell lengths	52.777, 71.058, 72.123
Unit cell angles	90.00, 90.00, 90.00

Refinement procedure

Resolution	20.000 - 2.300
R-factor	0.2457
Rwork	0.246
R-free	0.30390
Structure solution method	MOLECULAR REPLACEMENT
Data reduction software	DENZO
Data scaling software	SCALEPACK
Phasing software	AMoRE
Refinement software	CNS (1.1)

Data quality characteristics

	Overall
Low resolution limit [Å]	20.000
High resolution limit [Å]	2.300
Number of reflections	11571
Completeness [%]	93.7

Crystallization Conditions

crystal ID	method	pH	temperature	details
1	VAPOR DIFFUSION, HANGING DROP	7.4	277	0.2M HEPES, pH 7.4, VAPOR DIFFUSION, HANGING DROP, temperature 277K