3N46
Human FPPS complex with NOV_980 and zoledronic acid/MG2+
Experimental procedure
| Experimental method | SINGLE WAVELENGTH |
| Source type | SYNCHROTRON |
| Source details | SLS BEAMLINE X06SA |
| Synchrotron site | SLS |
| Beamline | X06SA |
| Temperature [K] | 105 |
| Detector technology | CCD |
| Collection date | 2004-09-02 |
| Detector | MAR CCD 165 |
| Wavelength(s) | 0.97936 |
| Spacegroup name | P 41 21 2 |
| Unit cell lengths | 110.853, 110.853, 70.861 |
| Unit cell angles | 90.00, 90.00, 90.00 |
Refinement procedure
| Resolution | 39.190 - 2.350 |
| R-factor | 0.21 |
| Rwork | 0.204 |
| R-free | 0.26600 |
| Structure solution method | FOURIER SYNTHESIS |
| RMSD bond length | 0.008 |
| RMSD bond angle | 1.300 |
| Data reduction software | XDS |
| Data scaling software | XSCALE |
| Phasing software | APRV |
| Refinement software | CNS |
Data quality characteristics
| Overall | Outer shell | |
| Low resolution limit [Å] | 100.000 | 2.410 |
| High resolution limit [Å] | 2.350 | 2.350 |
| Rmerge | 0.053 | 0.357 |
| Number of reflections | 18838 | 1335 |
| <I/σ(I)> | 20.99 | 5.7 |
| Completeness [%] | 99.4 | 99.7 |
| Redundancy | 7.1 | 7.1 |
Crystallization Conditions
| crystal ID | method | pH | temperature | details |
| 1 | VAPOR DIFFUSION, HANGING DROP | 5.3 | 292 | 1.2M sodium potassium phosphate, 25% glycerol, pH 5.3, VAPOR DIFFUSION, HANGING DROP, temperature 292K |
