3IGG
Novel CDK-5 inhibitors - crystal structure of inhibitor EFQ with CDK-2
Experimental procedure
Experimental method | SINGLE WAVELENGTH |
Source type | ROTATING ANODE |
Source details | RIGAKU RUH2R |
Temperature [K] | 100 |
Detector technology | IMAGE PLATE |
Detector | RIGAKU RAXIS II |
Wavelength(s) | 1.5418 |
Spacegroup name | P 21 21 21 |
Unit cell lengths | 53.470, 72.040, 72.040 |
Unit cell angles | 90.00, 90.00, 90.00 |
Refinement procedure
Resolution | 18.720 - 1.800 |
R-factor | 0.209 |
Rwork | 0.209 |
R-free | 0.25731 |
Structure solution method | FOURIER SYNTHESIS |
Refinement software | REFMAC |
Data quality characteristics
Overall | |
Low resolution limit [Å] | 50.000 |
High resolution limit [Å] | 1.800 |
Number of reflections | 25669 |
Crystallization Conditions
crystal ID | method | pH | temperature | details |
1 |