3HA6
Crystal structure of aurora A in complex with TPX2 and compound 10
Experimental procedure
| Experimental method | SINGLE WAVELENGTH |
| Source type | SYNCHROTRON |
| Source details | APS BEAMLINE 17-ID |
| Synchrotron site | APS |
| Beamline | 17-ID |
| Spacegroup name | P 31 2 1 |
| Unit cell lengths | 86.464, 86.464, 143.345 |
| Unit cell angles | 90.00, 90.00, 120.00 |
Refinement procedure
| Resolution | 25.000 - 2.360 |
| R-factor | 0.2254 |
| Rwork | 0.224 |
| R-free | 0.25242 |
| Structure solution method | MOLECULAR REPLACEMENT |
| RMSD bond length | 0.012 |
| RMSD bond angle | 1.173 |
| Refinement software | REFMAC (5.2.0019) |
Data quality characteristics
| Overall | |
| Low resolution limit [Å] | 50.000 |
| High resolution limit [Å] | 2.360 |
| Number of reflections | 22350 |
| Completeness [%] | 84.0 |
Crystallization Conditions
| crystal ID | method | pH | temperature | details |
| 1 |
