3EYG
Crystal structures of JAK1 and JAK2 inhibitor complexes
Experimental procedure
| Experimental method | SINGLE WAVELENGTH |
| Source type | SYNCHROTRON |
| Source details | AUSTRALIAN SYNCHROTRON BEAMLINE MX1 |
| Synchrotron site | Australian Synchrotron |
| Beamline | MX1 |
| Spacegroup name | C 2 2 21 |
| Unit cell lengths | 45.025, 88.218, 145.834 |
| Unit cell angles | 90.00, 90.00, 90.00 |
Refinement procedure
| Resolution | 18.870 - 1.900 |
| R-factor | 0.171 |
| Rwork | 0.169 |
| R-free | 0.21400 |
| RMSD bond length | 0.014 |
| RMSD bond angle | 1.535 |
| Refinement software | REFMAC (5.2.0019) |
Data quality characteristics
| Overall | |
| Low resolution limit [Å] | 20.080 |
| High resolution limit [Å] | 1.900 |
| Number of reflections | 26544 |
Crystallization Conditions
| crystal ID | method | pH | temperature | details |
| 1 |
