37OC

PLK4-T170D (inactive) in complex with Cpd15

This is a non-PDB format compatible entry.

Experimental procedure

Experimental method	SINGLE WAVELENGTH
Source type	SYNCHROTRON
Source details	ALS BEAMLINE 5.0.2
Synchrotron site	ALS
Beamline	5.0.2
Temperature [K]	100
Detector technology	PIXEL
Collection date	2023-10-27
Detector	PSI PILATUS 6M
Wavelength(s)	1.00
Spacegroup name	P 65
Unit cell lengths	106.716, 106.716, 48.614
Unit cell angles	90.00, 90.00, 120.00

Refinement procedure

Resolution	53.360 - 1.690
R-factor	0.1765
Rwork	0.176
R-free	0.19210
Structure solution method	MOLECULAR REPLACEMENT
RMSD bond length	0.011
RMSD bond angle	1.059
Data reduction software	XDS
Data scaling software	XDS
Refinement software	PHENIX ((1.21rc1_5084: ???))

Data quality characteristics

	Overall	Outer shell
Low resolution limit [Å]	53.360	1.700
High resolution limit [Å]	1.690	1.690
Rmerge	0.069
Number of reflections	35313	342
<I/σ(I)>	17.9
Completeness [%]	100.0
Redundancy	20
CC(1/2)	0.990	0.335

Crystallization Conditions

crystal ID	method	pH	temperature	details
1	VAPOR DIFFUSION, HANGING DROP		294	1.4 M sodium phosphate monobasic monohydrate/potassium phosphate dibasic