37OB

PLK4-T170D (inactive) in complex with Cpd34

This is a non-PDB format compatible entry.

Experimental procedure

Experimental method	SINGLE WAVELENGTH
Source type	SYNCHROTRON
Source details	ALS BEAMLINE 5.0.2
Synchrotron site	ALS
Beamline	5.0.2
Temperature [K]	100
Detector technology	PIXEL
Collection date	2023-10-27
Detector	PSI PILATUS 6M
Wavelength(s)	1.00
Spacegroup name	P 65
Unit cell lengths	106.556, 106.556, 48.475
Unit cell angles	90.00, 90.00, 120.00

Refinement procedure

Resolution	18.600 - 2.011
R-factor	0.2112
Rwork	0.209
R-free	0.24780
Structure solution method	MOLECULAR REPLACEMENT
RMSD bond length	0.008
RMSD bond angle	0.960
Data scaling software	XDS
Refinement software	BUSTER (2.11.8 (26-JUL-2023))

Data quality characteristics

	Overall	Outer shell
Low resolution limit [Å]	92.000	2.100
High resolution limit [Å]	2.000	2.000
Rmerge	0.110	3.400
Number of reflections	18537	170
<I/σ(I)>	14.7	0.9
Completeness [%]	99.0	96
Redundancy	13.7
CC(1/2)	0.990	0.280

Crystallization Conditions

crystal ID	method	pH	temperature	details
1	VAPOR DIFFUSION, HANGING DROP		294	1.4 M sodium phosphate monobasic monohydrate/potassium phosphate dibasic