2XHT
Structure of HSP90 with small molecule inhibitor bound
Experimental procedure
Experimental method | SINGLE WAVELENGTH |
Source type | ROTATING ANODE |
Temperature [K] | 100 |
Spacegroup name | P 1 21 1 |
Unit cell lengths | 53.505, 41.871, 54.202 |
Unit cell angles | 90.00, 116.11, 90.00 |
Refinement procedure
Resolution | 31.740 - 2.270 |
R-factor | 0.2286 |
Rwork | 0.225 |
R-free | 0.29690 |
Structure solution method | OTHER |
Starting model (for MR) | NONE |
Refinement software | BUSTER-TNT (2.5.1) |
Data quality characteristics
Overall | |
Low resolution limit [Å] | 31.570 |
High resolution limit [Å] | 2.300 |
Rmerge | 0.080 |
Number of reflections | 9778 |
Completeness [%] | 94.0 |
Redundancy | 2.4 |
Crystallization Conditions
crystal ID | method | pH | temperature | details |
1 |