2XAB
Structure of HSP90 with an inhibitor bound
Experimental procedure
| Experimental method | SINGLE WAVELENGTH |
| Source type | ROTATING ANODE |
| Source details | RIGAKU FR-E |
| Temperature [K] | 100 |
| Detector technology | CCD |
| Detector | RIGAKU CCD |
| Spacegroup name | P 21 21 2 |
| Unit cell lengths | 64.566, 89.208, 99.079 |
| Unit cell angles | 90.00, 90.00, 90.00 |
Refinement procedure
| Resolution | 43.310 - 1.900 |
| R-factor | 0.2056 |
| Rwork | 0.204 |
| R-free | 0.23620 |
| Structure solution method | OTHER |
| Starting model (for MR) | NONE |
| RMSD bond length | 0.013 |
| RMSD bond angle | 1.010 |
| Data reduction software | d*TREK |
| Refinement software | BUSTER-TNT (2.9.3) |
Data quality characteristics
| Overall | |
| Low resolution limit [Å] | 46.250 |
| High resolution limit [Å] | 1.900 |
| Rmerge | 0.110 |
| Number of reflections | 45815 |
| <I/σ(I)> | 6.3 |
| Completeness [%] | 98.6 |
| Redundancy | 3.31 |
Crystallization Conditions
| crystal ID | method | pH | temperature | details |
| 1 |
