2UZE
Crystal structure of human CDK2 complexed with a thiazolidinone inhibitor
Experimental procedure
Experimental method | SINGLE WAVELENGTH |
Source type | SYNCHROTRON |
Source details | ESRF BEAMLINE ID14-4 |
Synchrotron site | ESRF |
Beamline | ID14-4 |
Temperature [K] | 100 |
Detector technology | CCD |
Collection date | 2003-07-21 |
Detector | ADSC CCD |
Spacegroup name | C 1 2 1 |
Unit cell lengths | 212.626, 73.436, 153.028 |
Unit cell angles | 90.00, 129.54, 90.00 |
Refinement procedure
Resolution | 20.000 - 2.400 |
R-factor | 0.198 |
Rwork | 0.196 |
R-free | 0.24300 |
Structure solution method | OTHER |
RMSD bond length | 0.017 |
RMSD bond angle | 1.733 |
Data reduction software | DENZO |
Data scaling software | SCALEPACK |
Refinement software | REFMAC (5.2.0019) |
Data quality characteristics
Overall | |
Low resolution limit [Å] | 30.000 |
High resolution limit [Å] | 2.300 |
Rmerge | 0.090 |
Number of reflections | 70622 |
<I/σ(I)> | 8.6 |
Completeness [%] | 87.5 |
Redundancy | 2.4 |
Crystallization Conditions
crystal ID | method | pH | temperature | details |
1 | VAPOR DIFFUSION | 7 | 277 | VAPOUR DIFFUSION AT 4 DEG C, 0.1 M HEPES PH 7.0, 1M LITHIUM SULPHATE |