2UVZ

Structure of PKA-PKB chimera complexed with C-Phenyl-C-(4-(9H-purin-6- yl)-phenyl)-methylamine

Experimental procedure

Experimental method	SINGLE WAVELENGTH
Source type	ROTATING ANODE
Temperature [K]	100
Spacegroup name	P 21 21 21
Unit cell lengths	72.577, 74.661, 80.268
Unit cell angles	90.00, 90.00, 90.00

Refinement procedure

Resolution	27.330 - 1.940
R-factor	0.205
Rwork	0.203
R-free	0.24500
Structure solution method	MOLECULAR REPLACEMENT
RMSD bond length	0.007
RMSD bond angle	0.975
Refinement software	REFMAC (5.2.0019G)

Data quality characteristics

	Overall	Outer shell
Low resolution limit [Å]	27.300	1.970
High resolution limit [Å]	1.940	1.940
Rmerge	0.060	0.300
Number of reflections	30508
<I/σ(I)>	6.6	2.4
Completeness [%]	96.8	88.5
Redundancy	2.4	1.9

Crystallization Conditions

crystal ID	method	pH	temperature	details
1