2MSX
The solution structure of the MANEC-type domain from Hepatocyte Growth Factor Inhibitor 1 reveals an unexpected PAN/apple domain-type fold
Spectrometer
Experimental method: SOLUTION NMR
| Spectrometer ID | Spectrometer maker | Spectrometer model | Spectrometer type | Spectrometer field strength |
| 1 | Bruker | Plus | Bruker Plus | 500 |
| 2 | Agilent | DDR2 | Agilent DDR2 | 600 |
| 3 | Agilent | DDR2 | Agilent DDR2 | 800 |
Experiment
| experiment id | conditions id | solution id | Experiment type |
| 1 | 1 | 1 | 2D 1H-15N HSQC |
| 10 | 2 | 1 | 2D (HB)CB(CGCDCE)HE |
| 11 | 2 | 1 | 3D HBCB(CGCD)HD |
| 12 | 2 | 1 | 3D HBCB(CGCDCE)HE |
| 13 | 2 | 1 | 3D 13C-edited NOESY HSQC |
| 14 | 2 | 1 | 4D 13Cali,13Caro-edited HMQC-NOESY-HSQC |
| 15 | 2 | 1 | 4D 13Cali,13Cali-edited HMQC-NOESY-HMQC |
| 16 | 2 | 1 | 4D 15N,13C edited HMQC-NOESY-HSQC |
| 17 | 2 | 1 | 2D 1H-15N HSQC |
| 18 | 2 | 1 | 2D 1H-13C HSQC |
| 19 | 2 | 1 | 3D 1H-15N NOESY |
| 2 | 1 | 1 | 2D 1H-13C HSQC |
| 20 | 1 | 1 | 2D 1H-15N HSQC |
| 3 | 1 | 1 | 3D CBCA(CO)NH |
| 4 | 1 | 1 | 3D HNCACB |
| 5 | 1 | 1 | 3D HNCO |
| 6 | 1 | 1 | 3D HNCA |
| 7 | 2 | 1 | 4D HabCab(CO)NH |
| 8 | 2 | 1 | 4D HCCH-TOCSY |
| 9 | 2 | 1 | 2D (HB)CB(CGCD)HD |
NMR Sample
| conditions id | NMR sample pH | NMR sample pressure | NMR sample temperature |
| 1 | 6.5 | ambient | 310 |
| 2 | 6.5 | ambient | 298 |
Conformers
| Conformers Calculated Total Number | 80 |
| Conformers Submitted Total Number | 20 |
