2C6O

Crystal structure of the human CDK2 complexed with the triazolopyrimidine inhibitor

Refinement Statistics

Experimental method:X-RAY DIFFRACTION (2.1 Å)

Cell axes53.04271.76071.764
Cell angles90.0090.0090.00
SpacegroupP 21 21 21
Resolution limits29.75 - 2.10
the highest resolution shell value2.150 - 2.100
R-factor0.235
R-work0.23300
the highest resolution shell value0.282
R-free0.28800
the highest resolution shell value0.363
RMSD bond length0.028
RMSD bond angle2.454

Data Collection Statistics

Resolution limits30.00 - 2.00
the highest resolution shell value -
Number of reflections18445
Rmerge_l_obs0.050
the highest resolution shell value0.420
Completeness88.6
Redundancy2.29
the highest resolution shell value1.14

Crystallization Conditions

crystal IDmethodpHpH rangetemperatureunit
1VAPOR DIFFUSION, HANGING DROP7.2

Crystallization Reagents

IDcrystal IDsolution IDreagent nameconcentrationdetails
Crystallization Reagents in Literatures*
IDcrystal IDsolutionreagent nameconcentration (unit)details
Annotated Information is extracted from Literature Info*