2BUC

Crystal Structure Of Porcine Dipeptidyl Peptidase IV (CD26) in Complex with a Tetrahydroisoquinoline Inhibitor

Experimental procedure

Experimental method	SINGLE WAVELENGTH
Source type	SYNCHROTRON
Source details	SLS
Synchrotron site	SLS
Temperature [K]	100
Spacegroup name	P 1
Unit cell lengths	61.644, 117.491, 133.057
Unit cell angles	112.44, 94.72, 91.30

Refinement procedure

Resolution	19.280 - 2.500
R-factor	0.222
Rwork	0.221
R-free	0.27900
Structure solution method	OTHER
RMSD bond length	0.005
RMSD bond angle	0.908
Refinement software	REFMAC (5.1.24)

Data quality characteristics

	Overall
Low resolution limit [Å]	19.280
High resolution limit [Å]	2.500
Rmerge	0.200
Number of reflections	115542
Completeness [%]	97.1
Redundancy	1.98

Crystallization Conditions

crystal ID	method	pH	temperature	details
1