2XHR

Structure of HSP90 with small molecule inhibitor bound

Experimental procedure

Experimental method	SINGLE WAVELENGTH
Source type	ROTATING ANODE
Temperature [K]	100
Spacegroup name	I 2 2 2
Unit cell lengths	65.652, 89.559, 99.181
Unit cell angles	90.00, 90.00, 90.00

Refinement procedure

Resolution	36.200 - 2.200
R-factor	0.2532
Rwork	0.251
R-free	0.30360
Structure solution method	OTHER
Starting model (for MR)	NONE
Refinement software	BUSTER-TNT (2.5.1)

Data quality characteristics

	Overall
Low resolution limit [Å]	36.190
High resolution limit [Å]	2.200
Rmerge	0.100
Number of reflections	15199
Completeness [%]	99.2
Redundancy	2.5

Crystallization Conditions

crystal ID	method	pH	temperature	details
1