2WIH

STRUCTURE OF CDK2-CYCLIN A WITH PHA-848125

Experimental procedure

Experimental method	SINGLE WAVELENGTH
Source type	SYNCHROTRON
Source details	ESRF BEAMLINE ID14-4
Synchrotron site	ESRF
Beamline	ID14-4
Temperature [K]	100
Detector technology	CCD
Collection date	2008-04-28
Detector	ADSC CCD
Spacegroup name	P 62 2 2
Unit cell lengths	183.000, 183.000, 213.560
Unit cell angles	90.00, 90.00, 120.00

Refinement procedure

Resolution	29.960 - 2.500
R-factor	0.215
Rwork	0.213
R-free	0.25000
Structure solution method	OTHER
Starting model (for MR)	NONE
RMSD bond length	0.006
RMSD bond angle	0.900
Data reduction software	DENZO
Data scaling software	SCALEPACK
Refinement software	CNX

Data quality characteristics

	Overall	Outer shell
Low resolution limit [Å]	30.000	2.600
High resolution limit [Å]	2.500	2.500
Rmerge	0.090	0.570
Number of reflections	72932
<I/σ(I)>	16.1	3.7
Completeness [%]	99.7	100
Redundancy	7	0

Crystallization Conditions

crystal ID	method	pH	temperature	details
1				20% AMMONIUM SULPHATE, 1M KCL, 40MM HEPES PH 7