2WD1
Human c-Met Kinase in complex with azaindole inhibitor
Experimental procedure
| Experimental method | SINGLE WAVELENGTH |
| Source type | SYNCHROTRON |
| Source details | SLS BEAMLINE X06SA |
| Synchrotron site | SLS |
| Beamline | X06SA |
| Temperature [K] | 100 |
| Detector technology | PIXEL |
| Collection date | 2008-02-01 |
| Detector | DECTRIS PILATUS 6M |
| Spacegroup name | P 1 21 1 |
| Unit cell lengths | 37.411, 42.312, 84.826 |
| Unit cell angles | 90.00, 93.01, 90.00 |
Refinement procedure
| Resolution | 42.370 - 2.000 |
| R-factor | 0.212 |
| Rwork | 0.210 |
| R-free | 0.26500 |
| Structure solution method | MOLECULAR REPLACEMENT |
| RMSD bond length | 0.009 |
| RMSD bond angle | 1.148 |
| Data reduction software | XDS |
| Data scaling software | XSCALE |
| Phasing software | CCP4 |
| Refinement software | REFMAC (5.2.0005) |
Data quality characteristics
| Overall | Outer shell | |
| Low resolution limit [Å] | 42.370 | 2.100 |
| High resolution limit [Å] | 2.000 | 2.000 |
| Rmerge | 0.130 | 0.490 |
| Number of reflections | 18000 | |
| <I/σ(I)> | 12.43 | 4.22 |
| Completeness [%] | 99.1 | 99.4 |
| Redundancy | 4 | 4 |
Crystallization Conditions
| crystal ID | method | pH | temperature | details |
| 1 |
