2UVX

Structure of PKA-PKB chimera complexed with 7-azaindole

Experimental procedure

Experimental method	SINGLE WAVELENGTH
Source type	ROTATING ANODE
Temperature [K]	100
Spacegroup name	P 21 21 21
Unit cell lengths	72.537, 74.400, 79.869
Unit cell angles	90.00, 90.00, 90.00

Refinement procedure

Resolution	30.580 - 2.000
R-factor	0.175
Rwork	0.172
R-free	0.23700
Structure solution method	MOLECULAR REPLACEMENT
RMSD bond length	0.012
RMSD bond angle	1.316
Data reduction software	MOSFLM
Data scaling software	SCALA
Refinement software	REFMAC (5.2.0019G)

Data quality characteristics

	Overall	Outer shell
Low resolution limit [Å]	30.600	2.110
High resolution limit [Å]	2.000	2.000
Rmerge	0.070	0.290
Number of reflections	27518
<I/σ(I)>	9.6	2
Completeness [%]	97.5	93
Redundancy	2.4	2

Crystallization Conditions

crystal ID	method	pH	temperature	details
1