2JC1

CRYSTAL STRUCTURE OF HEPATITIS C VIRUS POLYMERASE IN COMPLEX WITH INHIBITOR SB698223

Experimental procedure

Experimental method	SINGLE WAVELENGTH
Source type	ROTATING ANODE
Source details	RIGAKU RUH2R
Temperature [K]	100
Detector technology	IMAGE PLATE
Detector	RIGAKU IMAGE PLATE
Spacegroup name	P 21 21 21
Unit cell lengths	86.240, 106.260, 126.400
Unit cell angles	90.00, 90.00, 90.00

Refinement procedure

Resolution	20.000 - 2.000
R-factor	0.193
Rwork	0.191
R-free	0.23300
Structure solution method	OTHER
RMSD bond length	0.013
RMSD bond angle	1.334
Data reduction software	DENZO
Data scaling software	SCALEPACK
Refinement software	REFMAC (5.3.0006)

Data quality characteristics

	Overall
Low resolution limit [Å]	27.400
High resolution limit [Å]	2.000
Rmerge	0.070
Number of reflections	74593
Completeness [%]	95.0
Redundancy	2.5

Crystallization Conditions

crystal ID	method	pH	temperature	details
1