2IWX
Analogues of radicicol bound to the ATP-binding site of Hsp90.
Experimental procedure
| Experimental method | SINGLE WAVELENGTH |
| Source type | SYNCHROTRON |
| Source details | ESRF BEAMLINE ID14-1 |
| Synchrotron site | ESRF |
| Beamline | ID14-1 |
| Temperature [K] | 100 |
| Detector technology | CCD |
| Collection date | 2006-02-19 |
| Detector | ADSC CCD |
| Spacegroup name | P 43 2 2 |
| Unit cell lengths | 73.703, 73.703, 110.019 |
| Unit cell angles | 90.00, 90.00, 90.00 |
Refinement procedure
| Resolution | 73.720 - 1.500 |
| R-factor | 0.2 |
| Rwork | 0.198 |
| R-free | 0.23600 |
| Structure solution method | OTHER |
| RMSD bond length | 0.012 |
| RMSD bond angle | 1.591 |
| Data reduction software | MOSFLM |
| Data scaling software | SCALA |
| Refinement software | REFMAC (5.2.0019) |
Data quality characteristics
| Overall | Outer shell | |
| Low resolution limit [Å] | 40.000 | 1.580 |
| High resolution limit [Å] | 1.500 | 1.500 |
| Rmerge | 0.080 | 0.250 |
| Number of reflections | 49255 | |
| <I/σ(I)> | 23.3 | 6.4 |
| Completeness [%] | 100.0 | 100 |
| Redundancy | 8.5 | 6.6 |
Crystallization Conditions
| crystal ID | method | pH | temperature | details |
| 1 |
